Imagine a sudden crisis within a country. One day, suddenly, there is a need to face an impending disaster. What happens? The people go into panic-mode and stop doing their regular jobs, and instead focus on averting the crisis. Normal production ceases, and things needed to face the disaster are produced. The pace of production is ramped, and irrespective of the quality, a huge quantity of emergency supplies is generated.
Like humans, cells in our body also face crisis. They need to adapt to extreme environments quickly in order to survive and thrive. Gesa, Alexandra, Lysann and colleagues wanted to know what happens to the cellular production process during the stress period. How does the cell switch to producing cell-responsive genes. And not only producing, but producing at a fast-pace. Are the quality controls applicable during normal times also applicable during the frantic response to stress. They find that the cell switches to stress-control mode, and for a certain time, eases on the quality controls of production. Please listen to Gesa on the interesting adaptability of the cells.
For more information, please refer to:
mRNA quality control is bypassed for immediate export of stress-responsive transcripts
Zander et al., Nature, 2016
Like humans, cells in our body also face crisis. They need to adapt to extreme environments quickly in order to survive and thrive. Gesa, Alexandra, Lysann and colleagues wanted to know what happens to the cellular production process during the stress period. How does the cell switch to producing cell-responsive genes. And not only producing, but producing at a fast-pace. Are the quality controls applicable during normal times also applicable during the frantic response to stress. They find that the cell switches to stress-control mode, and for a certain time, eases on the quality controls of production. Please listen to Gesa on the interesting adaptability of the cells.
For more information, please refer to:
mRNA quality control is bypassed for immediate export of stress-responsive transcripts
Zander et al., Nature, 2016
No comments:
Post a Comment