We live in a 3D world, in which every object occupies space. Same is true for all cells. The size of biological objects is a ubiquitous property, about which very less is known. How do cells 'measure' their size and how do they regulate it in response to changing environment? These unanswered questions have far-reaching implications on every aspect of biology.
Leigh Harris and her colleagues set out to discover the principles regulating cell size in a simple model, bacteria. She used live imaging and quantitative analysis to accurate measure bacterial cell volume and surface area: two parameters implicated in size control. Excitingly, she was able to come up with a simple ratio: the rate of surface area to volume change, which defines the steady state size and shape of the cell. This presents a novel unified model for regulating bacterial size. Lets call Leigh to understand more about this principle!
To know about the story, please read:
Relative Rates of Surface and Volume Synthesis Set Bacterial Cell Size
Leigh and Theriot, Cell, 2 June 2016.
Leigh Harris and her colleagues set out to discover the principles regulating cell size in a simple model, bacteria. She used live imaging and quantitative analysis to accurate measure bacterial cell volume and surface area: two parameters implicated in size control. Excitingly, she was able to come up with a simple ratio: the rate of surface area to volume change, which defines the steady state size and shape of the cell. This presents a novel unified model for regulating bacterial size. Lets call Leigh to understand more about this principle!
To know about the story, please read:
Relative Rates of Surface and Volume Synthesis Set Bacterial Cell Size
Leigh and Theriot, Cell, 2 June 2016.
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