Tuesday, May 31, 2016

Little things that can make a big difference -- Interview with Jane Freedman and Kahraman Tanriverdi about detecting small RNAs in blood!

RNA molecules - most of us might know them as middle men between the biological information storage unit: DNA, and the functional unit: protein. But a large numbers of small sized RNAs are important players in regulating genetic networks. These small RNAs, like micro-RNA, are capable of regulating a vast numbers of genes. These small RNAs are involved in almost every biological aspect, from development to disease. Wouldn't it be interesting to sense their presence to predict developmental or disease trajectories.

Now, Jane, Kahraman and their colleagues develop a sensitive assay capable of detecting and quantifying small RNAs in human blood samples. They use their technique to probe small RNAs presence in human blood samples and to detect their diversity among various groups. Their findings show a great deal of diversity in small RNAs presence, whose role would be most interesting to elucidate. To know more about the study, please listen to their interview:


To know more about the study, please refer to:
Diverse human extracellular RNAs are widely detected in human plasma
Freedman et al., Nature Communications, 2016.

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