Celebrating 100th birthday in good health! Who doesn't want that. With modern medicine, more and more people are living longer and healthier lives. And diet plays a major role in helping us live longer. Scientific evidence points more and more towards a low-calorie diet leading to increase in lifespan. But eating less to restrict calories is so tough! Everyone wants to have an ice-cream at the end of the day. Is it possible to eat indulgent food and still extend lifespan?
Tabrez and colleagues wanted to understand the basic biological changes that occur with dietary restriction. Illuminating the underlying principles would help harnessing them for increasing lifespan. They found that during dietary restriction, the genetic information processing is altered and this changes the biological landscape of the cells. Such alterations could help cells with efficient energy processing. To know more, please listen to Tabrez.
To know more, please refer to:
Differential alternative splicing coupled to nonsense-mediated decay of mRNA ensures dietary restriction-induced longevity
Tabrez et al., Nature communications, 2017
Tabrez and colleagues wanted to understand the basic biological changes that occur with dietary restriction. Illuminating the underlying principles would help harnessing them for increasing lifespan. They found that during dietary restriction, the genetic information processing is altered and this changes the biological landscape of the cells. Such alterations could help cells with efficient energy processing. To know more, please listen to Tabrez.
To know more, please refer to:
Differential alternative splicing coupled to nonsense-mediated decay of mRNA ensures dietary restriction-induced longevity
Tabrez et al., Nature communications, 2017
